This project seeks to support the realization of the sexual and reproductive health and rights (SRHR), well-being and dignity of marginalized adolescent girls and boys in all their diversity, in Dar es Salaam and Dodoma City Council. The Accelerated Hope and Development for Adolescents in Tanzania (AHADI) project focuses on supporting adolescents according to their age groups (10-14 years of age and 15-19 years of age) and works in five urban districts and their surrounding communities. Project activities include: (1) identifying and addressing barriers to health-related human rights for adolescent girls and boys; (2) supporting adolescent girls (10-19 years of age) in making informed decisions on nutrition, SRHR and sexual and gender-based violence (SGBV) protection services by enhancing the capacity of guardians, community influencers and community institutions, such as the police, to advocate for adolescent girls’ protection and the reduction of harmful traditional practices and norms; (3) enhancing the inclusive and equitable use of quality adolescent-friendly, gender-responsive and pandemic-responsive and resilient SRHR and nutrition services, including substance misuse prevention and iron and folic acid supplementation; (4) responding to the increased vulnerability of young girls to violence, unwanted pregnancy, disrupted health services and impacted livelihoods, as a result of the COVID-19 pandemic; (5) empowering the most vulnerable adolescent girls and boys (15-19 of years of age, including SGBV survivors, substance users, those living with disabilities, those living on the streets and those engaged in transactional sex) to participate in gender-equitable poverty reduction activities through the labour market and entrepreneurship programs; and (6) integrating a life skills and economic empowerment component to enable adolescent girls to have greater financial autonomy, reducing their poverty and the burden of unpaid care. The project seeks to directly reach 284,139 girls and 192,480 boys (approximately 60% of the adolescent population in the project area) and 137,487 women and 137,486 men caregivers, 1,000 women and 1,160 men faith/community leaders, 250 women and 250 men teachers, and 200 women and 200 men community health workers. An additional 183,315 girls and 122,210 boys will benefit indirectly.